From within the SEPM if you sync an AD container that has managed clients in a unsynched container it moves them to the synched container in the SEPM and will not allow you to move them back without breaking the client management.
This being said it would be very helpful to be able to scan AD for hosts & their client status if present with the option to deploy to selected unmanaged objects without breaking container structures of managed computers when moving them to unsynched. If its not feesable to do this from the SEPM a tool would be very helpful for this.