Would be useful in the cases of multiple SEPM environments and migration work if you were able to use location awareness to set which management server list you'd like a machine to report into and maybe be able to define location rules based on OS of clients.
For example moving clients to a new SEPM but you don't want the unsupported operating systems to move to the new environment. Then instead of creating a new group to move the machines into and having to go through all the orperating systems the location awareness and management server lists would do it all for you.